Personalized Genetic Testing and Norovirus Susceptibility

Personalized Genetic Testing and Norovirus Susceptibility

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BACKGROUND: The Soap Dock availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information.Various genetic traits can be determined including resistance to norovirus through a nonsense mutation (G428A) in the FUT2 gene.Although this trait is believed to confer resistance to the most dominant Course a pied - Accessoires - Hydratation - Bouteille norovirus genotype (GII.4), the spectrum of resistance to other norovirus strains is unknown.

The present report describes a cluster of symptomatic norovirus GI.6 infection in a family identified to have norovirus resistance through personalized genetic testing.